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    It’s best to continue to smoke in the first week of Zyban and set a quit date for some time in the second week. Zyban works best when you also work on the stress side of quitting and strategies to beat the habit, which is why combining Quitline with Zyban gives you the best chance of success.

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    https://www.nps.org.au/australian-prescriber/articles/bupropion
    Zyban (Glaxo Wellcome) 150 mg sustained-release tablets Approved indication: nicotine dependence Australian Medicines Handbook Section 18.6.2 Bupropion is not a new drug. It was approved in the USA for the treatment of depression more than 10 years ago. The antidepressant effect probably involves the drug's action on neurotransmitters.

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