Osteoblasts Support B Lymphocyte Commitment And Differentiation Of Hematopoietic Stem Cel

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Osteoblasts support B lymphocyte commitment and ...

    https://www.researchgate.net/profile/Russell_Taichman/publication/6574477_Osteoblasts_support_B-lymphocyte_commitment_and_differentiation_from_hematopoietic_stem_cells/links/00b7d528f50a09ea99000000.pdf?origin=publication_detail
    purified primary murine OB also support the differentiation of primitive hematopoietic stem cells through lymphoid commitment and subsequent differentiation to all stages of B cell precursors …

Interactions Between B Lymphocytes and the Osteoblast ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762579/
    Zhu et al. further demonstrated that calvarial osteoblasts in culture could support the full differentiation program of hematopoietic stem/progenitor cells into the B lymphocyte lineage, confirming a direct interaction between osteoblastic cells and B cell precursors .Cited by: 23

Osteoblasts support B-lymphocyte commitment and ...

    http://europepmc.org/abstract/MED/17227831
    Jun 01, 2007 · Previous studies had shown that osteoblasts (OBs) support hematopoietic stem cell (HSC) proliferation and myeloid differentiation. We now find that purified primary murine OBs also support the differentiation of primitive hematopoietic stem cells through lymphoid commitment and subsequent differentiation to all stages of B-cell precursors and mature B cells.Cited by: 339

(PDF) Osteoblasts support B-lymphocyte commitment and ...

    https://www.researchgate.net/publication/6574477_Osteoblasts_support_B-lymphocyte_commitment_and_differentiation_from_hematopoietic_stem_cells
    We now find that purified primary murine OBs also support the differentiation of primitive hematopoietic stem cells through lymphoid commitment and subsequent differentiation to all stages of B ...

The Role of Osteoblasts in the Hematopoietic ...

    https://stemcellsjournals.onlinelibrary.wiley.com/doi/full/10.1002/stem.160007
    Hematopoietic stem cell differentiation occurs in direct proximity to osteoblasts within the bone marrow cavity. Despite this striking affiliation, surprisingly little is known about the precise cellular and molecular impact of osteoblasts on the bone marrow microenvironment.Cited by: 245

Osteoblasts: a Novel Source of Erythropoietin

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349388/
    Osteoblasts, stromal cells, and endothelial cells then populate the vascularized bone marrow and produce chemokines and growth factors that recruit and maintain hematopoietic stem cells . Understanding the cellular and molecular cross talk in bone marrow microenvironment controlling bone formation and hematopoiesis is a rapidly growing area of research given the important implications for bone therapy…Cited by: 11



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