Mesenchymal Stem Cells Support Hematopoiesis

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Hepatic stellate cells support hematopoiesis and are liver ...

    https://www.ncbi.nlm.nih.gov/pubmed/23485574
    Hepatic stellate cells possess characteristics of stem/progenitor cells, but their contribution to hematopoiesis is not known thus far. METHODS: Isolated hepatic stellate cells from rats were characterized with respect to molecular markers of bone marrow mesenchymal stem cells (MSC) and treated with adipocyte or osteocyte differentiation media.Cited by: 80

Mouse mesenchymal stem cells can support human ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878784/
    We previously established a mesenchymal stem cell line (FMS/PA6-P) from the bone marrow adherent cells of fetal mice. The cell line expresses a higher level of neural cell adhesion molecule and shows greater hematopoiesis-supporting capacity in mice than other murine stromal cell lines. These ...Cited by: 18

Hematopoietic Support Capacity of Mesenchymal Stem Cells ...

    https://www.sciencedirect.com/science/article/pii/S0188440915002714
    Mesenchymal stem cells (MSCs) play an important role in the physiology and homeostasis of the hematopoietic system. Because MSCs generate most of the stromal cells present in the bone marrow (BM), form part of the hematopoietic stem cell (HSC) niche, and produce various molecules regulating hematopoiesis, their hematopoiesis-supporting capacity has been demonstrated.Cited by: 32

Interferon-Gamma Impairs Maintenance and Alters ...

    https://www.liebertpub.com/doi/full/10.1089/scd.2017.0196
    May 01, 2018 · Bone marrow (BM) mesenchymal stromal cells (MSCs) provide microenvironmental support to hematopoietic stem and progenitor cells (HSPCs). Culture-expanded MSCs are interesting candidates for cellular therapies due to their immunosuppressive and regenerative potential which can be further enhanced by pretreatment with interferon-gamma (IFN-γ).Cited by: 3

The Differentiation Balance of Bone Marrow Mesenchymal ...

    https://www.hindawi.com/journals/sci/2018/1540148/
    Bone marrow mesenchymal stem cells (BMSCs), the important component and regulator of bone marrow microenvironment, give rise to hematopoietic-supporting stromal cells and form hematopoietic niches for hematopoietic stem cells (HSCs). However, how BMSC differentiation affects hematopoiesis is …Cited by: 5

Human Embryonic Stem Cell-Derived Mesenchymal Stroma Cells ...

    https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055319
    Human Embryonic Stem Cell-Derived Mesenchymal Stroma Cells (hES-MSCs) Engraft In Vivo and Support Hematopoiesis without Suppressing Immune Function: Implications for Off-The Shelf ES-MSC Therapies. Ou Li,Cited by: 28



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