Searching for Bioartificial Liver Support information? Find all needed info by using official links provided below.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649611/
In conclusion, the approach of bioartificial liver support in combination with artificial devices is promising but several challenging tasks, such as identifying the ideal cell source and the agreement on a more uniform study design, still remain.
https://onlinelibrary.wiley.com/doi/10.1007/s005340170045
The history of extracorporeal bioartificial liver (BAL) support began in the late 1950s, when Sorrentino 41 first used the term “fegato artificiale” (“artificial liver”) while describing a series of in‐vitro experiments demonstrating that fresh liver tissue homogenates can metabolize salicylic and barbituric acid, and ketone bodies, and produce urea from ammonia.Cited by: 108
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356396/
The Bioartificial Liver Support System (BLSS) device, 80,81 developed in Pittsburgh, PA, uses 70 to 120 g of primary porcine hepatocytes. The hepatocytes, mixed with 20% collagen, are housed in an extrafiber space. Whole blood is perfused through the fibers of …Cited by: 268
https://medcaretips.com/bioartificial-liver/
In most bioartificial liver support devices, the liver cells are separated from the patient’s blood or plasma by at least one membrane to provide an immunological barrier. But it also limits the exchange of substances and therefore potentially reduces the effectiveness of the system.
http://experimental-surgery.de/Projects/bioartificial_liver/
An extracorporeal liver support system has to support or substitute the main functions of the liver, providing detoxification (e.g. toxins, ammonia, bilirubin, endotoxins), synthesis (e.g. albumin, amino acids, coagulation factors) and regulation (e.g. acid-base-status, electrolytes, amino acids,...
https://www.researchgate.net/publication/11958192_Bioartificial_Liver_Support
Bioartificial liver support is a promising technology, and the results of current and planned studies are awaited with great interest.
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