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https://www.freseniusmedicalcare.com/fileadmin/data/masterContent/pdf/Prometheus/Prometheus_Product_Range.pdf
Prometheus® Citrate Arterial and venous tubing system for liver support 5 501 777 1 Primary circuit (blood) therapy with citrate/calcium anticoagulation Prometheus® Secondary circuit (plasma) and reinfusion line 5 501 776 1 Secondary Circuit Prometheus® Arterial and …
https://www.therapeutic-apheresis.com/en/products/prometheus/
The Prometheus ® 4008H therapy system fulfils two important therapeutic functions, dialysis and adsorption, in one machine. The Prometheus ® device is based on Fresenius Medical Care’s well-established dialysis system 4008H. Prometheus ® combines an …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774070/
The development of these devices has been approached in two very different ways. The biological devices, which aim to provide all of the functions of the normal liver, 3, 4 are based on the use of living liver cells with either human hepatic cells as in the extracorporeal liver assist device (ELAD) device 5 or porcine hepatocytes as in the BAL device 6 and in various other European devices ...Cited by: 92
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1550821/
Feb 08, 2006 · Molecular Adsorbent Recirculating System. MARS ® is a liver support system that uses an albumin-enriched dialysate to facilitate the removal of albumin-bound toxins. The system has three different fluid compartments: a blood circuit, a circuit containing 600 ml of 20% human albumin with a charcoal column and an anion exchange resin column and a dialysate circuit [].Cited by: 28
https://www.sciencedirect.com/science/article/pii/S0168827803004689
Background/Aims: Extracorporeal detoxification systems for supportive therapy of liver failure have recently gained much interest.We herein report results from the first clinical application of Prometheus ®, a new liver support system in which albumin-bound substances are directly removed from blood by special adsorber.In a simultaneous step, high-flux hemodialysis is performed.Cited by: 351
https://clinicaltrials.gov/ct2/show/NCT00655304
The pathogenesis behind ICH is incompletely understood and the therapeutic options are limited. Prometheus (R) liver support dialysis offers a system that apart from regular high-flux hemodialysis to a certain extent is able of removing albumin-bound substances from the patient - a feature that theoretically could benefit patients with ALF.
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