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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707421/
Apr 11, 2013 · A fraction of native and all cultured pericytes express α-SMA, 29 therefore these findings also support a myofibroblastic identity for human hematopoietic stromal cells. 51 Besides a functional ability to support hematopoietic cells following dissociation, purification, and culture, human CD146 + perivascular cells from nonhematopoietic tissues share a similar phenotype with the perivascular niche cells recently described in murine bone marrow. 35-37 Perivascular cells …Cited by: 152
https://www.ncbi.nlm.nih.gov/pubmed/23412095
Apr 11, 2013 · Mesenchymal stem/stromal cells (MSCs), which support hematopoiesis in culture, are themselves derived in part from perivascular cells. In order to define their direct role in hematopoiesis, we tested the ability of purified human CD146(+) perivascular cells, as compared with unfractionated MSCs and CD146(-) cells, to sustain human HSPCs in coculture.Cited by: 152
https://www.researchgate.net/publication/235629319_Perivascular_support_of_human_hematopoietic_cells
Moreover, CD146+ perivascular cells express, natively and in culture, molecular markers of the vascular hematopoietic niche. Unexpectedly, this dramatic, previously undocumented ability to support hematopoietic stem cells is present in CD146+ perivascular cells extracted from the non-hematopoietic adipose tissue.
http://basicmed.med.ncku.edu.tw/public/project/1281-1363133644-1.pdf
CD146+ perivascular cells support the long-term persistence, through cell-to-cell contact and at least partly via Notch activation, of human myelo-lymphoid HSPCs able to engraft primary and secondary immunodeficient mice.
https://www.nature.com/articles/s12276-019-0357-5
12 days ago · A recent study reported that nonhematopoietic adipose tissue-derived PVCs support the long-term maintenance of human ... Kim, J. et al. BMP4 and perivascular cells promote hematopoietic ...Author: Suji Jeong
https://www.cirm.ca.gov/about-cirm/publications/perivascular-support-human-hematopoietic-stemprogenitor-cells
Mesenchymal stem/stromal cells (MSCs), which support hematopoiesis in culture, are themselves derived in part from perivascular cells. In order to define their direct role in hematopoiesis, we tested the ability of purified human CD146(+) perivascular cells, as compared with unfractionated MSCs and CD146(-) cells, to sustain human HSPCs in coculture.
http://www.crm.ed.ac.uk/publications/perivascular-support-human-hematopoietic-stem/progenitor-cells
Mesenchymal stem/stromal cells (MSCs), which support hematopoiesis in culture, are themselves derived in part from perivascular cells. In order to define their direct role in hematopoiesis, we tested the ability of purified human CD146(+) perivascular cells, as compared with unfractionated MSCs and CD146(-) cells, to sustain human HSPCs in coculture.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707421/
Apr 11, 2013 · A fraction of native and all cultured pericytes express α-SMA, 29 therefore these findings also support a myofibroblastic identity for human hematopoietic stromal cells. 51 Besides a functional ability to support hematopoietic cells following dissociation, purification, and culture, human CD146 + perivascular cells from nonhematopoietic ...Cited by: 152
https://www.ncbi.nlm.nih.gov/pubmed/23412095
Apr 11, 2013 · Perivascular support of human hematopoietic stem/progenitor cells. Corselli M(1), Chin CJ, Parekh C, Sahaghian A, Wang W, Ge S, Evseenko D, Wang X, Montelatici E, Lazzari L, Crooks GM, Péault B. Author information: (1)Orthopaedic Hospital, Department of Orthopaedic Surgery, University of California at Los Angeles (UCLA), CA, USA.Cited by: 152
https://www.researchgate.net/publication/235629319_Perivascular_support_of_human_hematopoietic_cells
Perivascular support of human hematopoietic cells. ... CD146+ perivascular cells support the long-term persistence, through cell-to-cell contact and …
https://www.cirm.ca.gov/about-cirm/publications/perivascular-support-human-hematopoietic-stemprogenitor-cells
The identity of the subset of human MSCs involved in hematopoietic support has been so far unknown. In the present study, Corselli et al. identified for the first time CD146+ perivascular cells as the subset of MSCs able to maintain hematopoietic stem and …
http://basicmed.med.ncku.edu.tw/public/project/1281-1363133644-1.pdf
Moreover, CD146+ perivascular cells express, natively and in culture, molecular markers of the vascular hematopoietic niche. Unexpectedly, this dramatic, previously undocumented ability to support hematopoietic stem cells is present in CD146+ perivascular cells extracted from the non-hematopoietic adipose tissue.
https://www.cirm.ca.gov/printpdf/16211
identity of the subset of human MSCs involved in hematopoietic support has been so far unknown. In the present study, Corselli et al. identified for the first time CD146+ perivascular cells as the subset of MSCs able to maintain hematopoietic stem and progenitor cells (HSPCs) after ex vivo culture. The authors first demonstrate that CD146 ...
https://www.nature.com/articles/s12276-019-0357-5
13 days ago · A recent study reported that nonhematopoietic adipose tissue-derived PVCs support the long-term maintenance of human ... Kim, J. et al. BMP4 and perivascular cells promote hematopoietic ...Author: Suji Jeong, Borim An, Jung-Hyun Kim, Hyo-Won Han, Hye-Ryeon Heo, Kwon-Soo Ha, Eun-Taek Han, Won Sun ...
http://europepmc.org/abstract/MED/23412095
May 01, 2013 · Moreover, CD146(+) perivascular cells express, natively and in culture, molecular markers of the vascular hematopoietic niche. Unexpectedly, this dramatic, previously undocumented ability to support hematopoietic stem cells is present in CD146(+) perivascular cells extracted from the nonhematopoietic adipose tissue.Cited by: 152
https://www.sciencedirect.com/science/article/pii/S1934590908003378
A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs ... Intriguingly, cultured human perivascular cells from either skeletal muscle, pancreas ... (data not shown). These cells therefore appear to be developmentally closer to MSCs than MAPCs or ESCs. In support of a perivascular origin of MSCs, we have also observed that ...Cited by: 3405
https://www.researchgate.net/profile/Gay_Crooks/publication/235629319_Perivascular_support_of_human_hematopoietic_cells/links/56e86d6008ae9bcb3e1cd1e2.pdf?origin=publication_list
Regular Article HEMATOPOIESIS AND STEM CELLS Perivascular support of human hematopoietic stem/progenitor cells Mirko Corselli,1,2 Chee Jia Chin, 3Chintan Parekh,4 Arineh Sahaghian, Wenyuan Wang,5 ...
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