Neurotrophic Support

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Neurotrophic Support and Oxidative Stress: Converging ...

    https://journals.sagepub.com/doi/10.1177/1073858408325269
    Nov 13, 2008 · Neurotrophic factors act to up-regulate antioxidant enzymes and promote the expression of antioxidant proteins. On the other hand, oxidative stress can cause down-regulation of neurotrophic factors. We propose that normal functioning of the nervous systems involves a positive feedback loop between antioxidant processes and neurotrophic support.Cited by: 66

Neurotrophic Support SpringerLink

    https://link.springer.com/referenceworkentry/10.1007%2F978-3-642-28753-4_201431
    This neurotrophic support may be supplied directly by cells of the target organ for the neuron, other cells adjacent to the axon or cell body or via the blood supply. Changes in neurotrophic support can induce changes in phenotype such as altered patterns of …

Neurotrophic Factors - an overview ScienceDirect Topics

    https://www.sciencedirect.com/topics/medicine-and-dentistry/neurotrophic-factors
    Many neurotrophic and growth factors are present in the substantia nigra and/or the striatum. Experimental evidence shows that several of these neurotrophic factors support the survival and differentiation of mesencephalic dopaminergic neurones. These factors include epidermal growth factor, basic fibroblast growth factor, brain-derived ...

Neurotrophic Hypothesis - BrainKart

    https://www.brainkart.com/article/Neurotrophic-Hypothesis_24783/
    Sep 22, 2017 · Neurotrophic Hypothesis. There is substantial evidence that nerve growth factors such as brain-derived neurotrophic factor (BDNF) are critical in theregulation of neural plasticity, resilience, and neurogenesis.The evidence suggests that depression is associated with the loss of neurotrophic support and that effective antidepressant therapies increase neurogenesis and synaptic connectivity …

Huntingtin controls neurotrophic support and survival of ...

    https://www.ncbi.nlm.nih.gov/pubmed/15242649
    Jul 09, 2004 · Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Gauthier LR(1), Charrin BC, Borrell-Pagès M, Dompierre JP, Rangone H, Cordelières FP, De Mey J, MacDonald ME, Lessmann V, Humbert S, Saudou F.Cited by: 1000

Huntingtin Controls Neurotrophic Support and Survival of ...

    https://www.sciencedirect.com/science/article/pii/S0092867404006191
    Jul 09, 2004 · Finally, we find that the polyQ-huntingtin-induced transport deficit results in the loss of neurotrophic support and neuronal toxicity. Our findings indicate that a key role of huntingtin is to promote BDNF transport and suggest that loss of this function might contribute to pathogenesis.Cited by: 1000

Neurotrophic Keratitis - NORD (National Organization for ...

    https://rarediseases.org/rare-diseases/neurotrophic-keratitis/
    In more advanced neurotrophic keratitis, surgeons will surgically transplant a single layer or multiple layers of the amniotic membrane onto the surface of the cornea. Neurotrophic keratitis can be treated with special contact lenses called scleral or corneal contact lenses. The scleral lens is dome-shaped and vaults over the cornea.

Current advances in using neurotrophic factors to treat ...

    https://translationalneurodegeneration.biomedcentral.com/articles/10.1186/2047-9158-1-14
    Jul 26, 2012 · Neurotrophic factors or neurotrophins are a group of growth factors which have been classically described for their ability to regulate differentiation and to support growth during development of the vertebrate nervous system.Cited by: 128



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