Searching for Metabolic Pathway Alterations That Support Cell Proliferation information? Find all needed info by using official links provided below.
https://www.ncbi.nlm.nih.gov/pubmed/22262476
Metabolic pathway alterations that support cell proliferation. Vander Heiden MG(1), Lunt SY, Dayton TL, Fiske BP, Israelsen WJ, Mattaini KR, Vokes NI, Stephanopoulos G, …Cited by: 212
http://symposium.cshlp.org/content/76/325.full.pdf
illustrating how metabolic pathways are regulated in pro-liferating cells to generate some of the key molecules needed to support growth. We also discuss how both genetic and environmental factors can influence the reg-ulation of these pathways to promote cell proliferation in different contexts. THE REQUIREMENTS OF ANABOLIC METABOLISM
http://symposium.cshlp.org/content/76/325.long
However, the incremental increase in ATP demand necessary to support proliferation is small relative to the large ATP consumption needed by all cells to support metabolic processes in the absence of proliferation (Kilburn et al. 1969; Locasale and Cantley 2010; Lunt and Vander Heiden 2011). Therefore, we hypothesize that proliferative cell ...
http://symposium.cshlp.org/content/76/325.full.pdf+html
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https://www.nature.com/articles/s42255-019-0032-0
Feb 11, 2019 · A key question when comparing the metabolism of specialized cell types is how to distinguish the metabolic alterations accompanying differences in growth and proliferation from the metabolic ...Cited by: 11
https://www.ncbi.nlm.nih.gov/pubmed/31020046
Metabolic alterations and the potential for targeting metabolic pathways in the treatment of multiple myeloma. ... Particular focus is given to metabolic alterations that contribute to myeloma cell growth, proliferation and drug resistance. Finally, novel approaches that target metabolic pathways for the treatment of MM are discussed.Author: Dustin Rizzieri, Barry Paul, Yubin Kang
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004916/
In a pathological context, it is currently well established that cancer growth and invasion also involves major alterations of cells’ metabolism. A common regulatory pathway exists therefore between cell proliferation and metabolism to insure a coordinated cellular response.Cited by: 155
https://www.pnas.org/content/116/1/52
Jan 02, 2019 · Tumor cells reprogram their metabolism to support cell growth, proliferation, and differentiation, thus driving cancer progression. Profiling of the metabolic signatures in heterogeneous tumors facilitates the understanding of tumor metabolism and introduces potential metabolic vulnerabilities that might be targeted therapeutically. We proposed a spatially resolved metabolomics …Cited by: 13
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989334/
Aug 18, 2016 · Intense examination of tumors and cancer cell lines has confirmed that many cancer-associated metabolic phenotypes allow robust growth and survival; however, little attention has been given to explicitly identifying the biochemical requirements for cell proliferation in a rigorous manner in the context of cancer metabolism.Cited by: 42
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