Lod Support Interval

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R: LOD support interval

    http://www.ugrad.stat.ubc.ca/R/library/qtl/html/lodint.html
    LOD units to drop to form the interval. Value An object of class scanone , like the input, indicating the position with the maximum LOD, and indicating approximate endpoints for the LOD support interval.

lodint function R Documentation

    https://www.rdocumentation.org/packages/qtl/versions/1.42-8/topics/lodint
    LOD units to drop to form the interval. lodcolumn. An integer indicating which of the LOD score columns should be considered (if input results are from scanone). expandtomarkers. If TRUE, the interval is expanded to the nearest flanking markers.

lodint: LOD support interval in qtl: Tools for Analyzing ...

    https://rdrr.io/cran/qtl/man/lodint.html
    LOD units to drop to form the interval. lodcolumn: An integer indicating which of the LOD score columns should be considered (if input results are from scanone). expandtomarkers: If TRUE, the interval is expanded to the nearest flanking markers.

A shorter tour of R/qtl

    https://rqtl.org/rqtltour2.pdf
    Interval estimates of the location of QTL are commonly obtained via 1.5-LOD support intervals, which may be calculated via the function lodint. Alternatively, an approximate Bayes credible interval may be obtained with bayesint. 29. To obtain the 1.5-LOD support interval and 95% Bayes interval for the QTL on chromosome 7, type: lodint(out.hk ...

Comparison of several confidence intervals for QTL ...

    https://www.nature.com/articles/hdy199757
    The confidence interval for the map location of quantitative trait loci (QTL) is a very important quantity for geneticists. The one LOD support interval has been proved to be a biased confidence ...Cited by: 21

LOD Intervals with Multiple QTL Mapping in r-qtl

    https://www.biostars.org/p/131005/
    I would like to get either a Bayes interval or a 1.5 LOD support interval, but the book I am using (A Guide to QTL Mapping with R/qtl) seems to indicate that both these functions assume a single QTL per trait. I would assume that with multiple QTL mapping you get multiple significant peaks and thus multiple intervals.

R/qtl tutorial - Biostatistics and Medical Informatics

    https://www.biostat.wisc.edu/~kbroman/teaching/misc/Hyderabad/rqtltour3.pdf
    Interval estimates of the location of QTL are commonly obtained via 1.5-LOD support intervals, which may be calculated via the function lodint(). Alternatively, an approximate Bayes credible interval may be obtained with bayesint(). 29. To obtain the 1.5-LOD support interval and 95% Bayes interval for the QTL on chromosome 7, type: lodint(out ...

6.3 Haplotype Analysis - John P. Hussman Institute for ...

    http://hihg.med.miami.edu/code/http/modules/education/Design/Print.asp?CourseNum=3&LessonNum=6
    Note that the interval between D5S178 and D5S210 has a lod score that maximizes at approximately 18. This interval between D5S178 and D5S210 is outside the approximate 99% confidence interval for disease gene localization because it does not fall within the three-lod unit support interval.

Confidence Intervals in QTL Mapping by Bootstrapping

    https://www.genetics.org/content/genetics/143/2/1013.full.pdf
    LOD drop-off support interval: For limited combinations of parameters, confidence intervals were calculated also with the LOD drop-off method. In these cases, a putative QTL wdS fitted at 1-cM intervals, and a support interval was constructed by taking the interval corresponding to …Cited by: 658



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