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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649611/
The fact that liver failure constitutes a life-threatening condition and can, in most cases, only be overcome by orthotopic liver transplantation, lead to the development of various artificial and bioartificial liver support devices. While artificial systems are based on the principles of adsorption ...
https://journals.lww.com/co-criticalcare/Abstract/2008/04000/Liver_support_devices.15.aspx
Purpose of review Liver support devices are used either as a bridge to liver transplantation or liver recovery in patients with acute or acute-on-chronic liver failure.The review analyzes the recent literature and asks if the current enthusiasm for these devices is justified. Recent findings Many liver support devices exist and are discussed. . Clinical data on artificial devices are rapidly ...
https://en.wikipedia.org/wiki/Bioartificial_liver_device
The purpose of BAL-type devices, currently, is not to permanently replace liver functions, but to serve as a supportive device, either allowing the liver to regenerate properly upon acute liver failure, or to bridge the individual's liver functions until a transplant is possible. FunctionSpecialty: internal medicine
https://www.ncbi.nlm.nih.gov/pubmed/11385970/
The biologic component of these hybrid liver support devices may consist of liver slices, granulated liver, or hepatocytes from low-grade tumor cells or porcine hepatocytes. These biologic components are housed within bioreactors. Currently the most clinically studied bioreactors are those that use capillary hollow-fiber systems.Cited by: 58
https://aasldpubs.onlinelibrary.wiley.com/doi/full/10.1002/lt.24396
Jan 19, 2016 · Mortality in patients with liver failure who cannot be rescued with liver transplantation remains high despite improvements in supportive care. 1 The fundamental thinking behind the use of extracorporeal liver support devices (ELSDs) is the idea that if the patient's liver and extrahepatic organs can be supported long enough, recovery should be ...Cited by: 14
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