Searching for Lcaa Cpg Support information? Find all needed info by using official links provided below.
https://en.wikipedia.org/wiki/Oligonucleotide_synthesis
To make the solid support material suitable for oligonucleotide synthesis, non-nucleosidic linkers or nucleoside succinates are covalently attached to the reactive amino groups in aminopropyl CPG, LCAA CPG, or aminomethyl MPPS. The remaining unreacted amino groups are capped with acetic anhydride. Typically, three conceptually different groups ...
http://www.linktech.co.uk/products/dna_solid_supports
Our high quality SynBase™ CPG support for solid phase synthesis of oligonucleotides has been designed to offer optimum performance depending on the application, and the required nucleoside loading and length of sequence (see Choosing A SynBase™ Solid Support for further information). SynBase™ is available in three pore sizes, 500Å, 1000Å and 3000Å.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1074720/
Apr 06, 2005 · Thus, each tandem synthesis performed two linker phosphoramidite additions, one coupling to begin the first primer on an underivatized LCAA-CPG support, and a second coupling to begin the second (5′-dye-primer) sequence on the 5′ end of the first primer.Cited by: 12
http://www.primesynthesis.com/oligonucleotide-synthesis
Controlled Pore Glass (CPG) has been widely used as a solid support for oligonucleotide (oligo) synthesis for over two decades. Prime Synthesis has perfected CPG for maximum oligo purity and yield. Our early research was awarded funding by the Ben Franklin Technology Partners Group. The outcome of this work was an in-depth understanding of how ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC373346/
Underivatized amino LCAA-CPG support (∼10 mg for a 0.2 µmol scale or ∼40 mg for a 1 µmol scale) was accurately weighed into ABI synthesis columns. Linker phosphoramidite solutions 13 were installed on spare base positions 5–8. Sequences were entered with an additional ‘fake’ 3′-base to work around the software’s expectation of ...Cited by: 15
https://www.sigmaaldrich.com/catalog/product/sigma/l8638
Application Long chain alkylamine controlled pore glass is used in chromatography. Long chain alkylamine controlled pore glass has been used to develop a novel method for the immobilization of nucleotides and for the synthesis of DNA oligonucleotides and their 3′- or (3′,5′)-conjugates.
https://www.chemgenes.com/search.php?q=CPG
By starting out as a supplier of 'Ultra Pure Products' and then also by becoming an active Contract Researcher, ChemGenes Corporation has achieved unparalled expertise in the field of DNA/RNA synthesis. Thus, all of us at ChemGenes have the opportunity and great pleasure to serve a vast number of scientists in the US and all over the world.
https://www.sciencedirect.com/science/article/pii/S0960894X0080400X
The conventional method5 of derivatising LCAA-CPG involves the dicyclohexylcarbodiimide (DCC) mediated synthesis of pentachlorophenyl or p-nttrophenyl active ester of appropriately protected deoxynucleoside-3'-0-succinates which in the subsequent condensation reaction with primary amino groups of LCAA-CPG gives the desired functionalised support.Cited by: 1
https://deepblue.lib.umich.edu/bitstream/handle/2027.42/143722/cpnc0302.pdf?sequence=1&isAllowed=y
LCAA-CPG support, S.5, is very easy to prepare, and this approach minimizes consump-tion of rare and expensive nucleosides. The two protocols using the Q-linker require a …
http://www.cs.unc.edu/~montek/dimpanbhatia/Nucleosides-Nucleotides-1995.pdf
deoxyribonucleoside-3'-O-succinates to LCAA-CPG, widely used support for solid phase oligonucleotide synthesis. The method involves the reaction of nucleoside-3'-O-succinates with aminoalkyl functions of the support in the presence of improved and commercially availableCited by: 16
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