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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413841/
Despite widespread use, the evidence base for the use of inotropes and vasopressors in critically ill patients is limited. Clearly, many patients would not survive without inotropic support, but there is, nonetheless, considerable variation in clinical practice.Cited by: 115
https://www.pharmaceutical-journal.com/learning/learning-article/use-of-inotropes-in-critical-care/11049283.fullarticle
Isoprenaline has a similar profile to dobutamine but tends to cause more tachycardia. It is sometimes used for bradycardic patients requiring inotropic support. Noradrenaline. Because noradrenaline acts primarily via a 1 receptors, it is usually used as a vasopressor (increasing SVR to maintain MAP) rather than an inotrope. It is often used ...
https://www.ncbi.nlm.nih.gov/pubmed/7686461
Inotropic support of the critically ill patient. A review of the agents. Kulka PJ(1), Tryba M. Author information: (1)Universitätsklinik für Anaesthesiologie, Intensiv- und Schmerztherapie, Berufsgenossenschaftliche Krankenanstalten Bergmannsheil, Bochum, Federal Republic of Germany.Cited by: 31
https://www.drugs.com/drug-class/inotropic-agents.html
Inotropic agents are a group of medicines that affect the contraction of the heart muscle. Technically, inotropes can be divided into positive inotropes, which stimulate and increase the force of contraction of the heart muscle, and negative inotropes, which weaken the force of muscular contractions, decreasing how hard the heart has to work.
https://www.aci.health.nsw.gov.au/__data/assets/pdf_file/0009/306585/Inotropes_and_Vasoconstictor_Package.pdf
inotropic support and administer infusion of vasopressors to maintain SBP and MAP and hence prevent organ ischemia and injury. Host infection (Bacterial, viral, fungal) ... In some of the ICU patients the maintenance of blood pressure is extremely dependant on the inotropes and vasopressor
https://www.uptodate.com/contents/use-of-vasopressors-and-inotropes
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https://globalrph.com/drugs/vasopressors-and-inotropes/
Used to support BP, CO and renal perfusion in shock. IMPORTANT NOTE: Renal shutdown may occur at doses greater than 50 micrograms/kilogram/minute. The infusion rate should be reduced if urine flow decreases without adequate peripheral effects. Administer into large vein to prevent the possibility of extravasation (central line administration).
https://www.ahajournals.org/doi/abs/10.1161/circulationaha.107.728840
49 Hershberger RE, Nauman D, Walker TL, Dutton D, Burgess D. Care processes and clinical outcomes of continuous outpatient support with inotropes (COSI) in patients with refractory endstage heart failure. J Card Fail. 2003; 9: 180–187. Crossref Medline Google ScholarCited by: 323
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