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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733230/
Mar 12, 2015 · Genetically, 80% of individuals with giant cell tumor of bone exhibit the cytogenetic abnormality of teleomeric associations (tas), whereas half of the cells in the tumor show the tas abnormality (1,31). The RANK pathway is often reported to …Cited by: 29
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989131/
Giant cell tumor (GCT) of bone is one of the commonest benign bone tumors encountered by an orthopedic surgeon. The reported incidence of GCT in the Oriental and Asian population is higher than that in the Caucasian population and may account for 20% of all skeletal neoplasms. 1,2 It has a well-known propensity for local recurrence after surgical treatment.
https://en.wikipedia.org/wiki/Giant-cell_tumor_of_bone
Giant-cell tumor of the bone (GCTOB), is a relatively uncommon tumor of the bone. It is characterized by the presence of multinucleated giant cells (osteoclast-like cells).Malignancy in giant-cell tumor is uncommon and occurs in about 2% of all cases.Specialty: Oncology
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